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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 11.52
Human Site: S199 Identified Species: 16.89
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S199 S Y L H S T Y S S Q P A P A L
Chimpanzee Pan troglodytes XP_001153855 674 74011 T144 V V I H K E A T V F D L P K F
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S199 S Y L H S T Y S S Q P A P A L
Dog Lupus familis XP_545496 695 74019 S165 P P A D A S A S I G S S P G V
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S199 S Y L H S T Y S S Q A T P A L
Rat Rattus norvegicus Q6GX84 677 74178 F147 M C K E P T I F E V P Q L G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 V200 A V G E G P P V P G L P S Q R
Chicken Gallus gallus Q5ZK92 613 66247 L83 L G L L V A W L C E R L S R G
Frog Xenopus laevis Q6DDU8 655 72133 R124 Q E M A E A G R R A Q L S L L
Zebra Danio Brachydanio rerio Q503S1 736 79183 H199 S P H P S P L H S A G L L Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530
Honey Bee Apis mellifera XP_625184 585 66969 Q55 S K I N N N P Q E W K S G L Y
Nematode Worm Caenorhab. elegans O16299 594 66169 P64 S D S A Q Q Q P P F K S R S Q
Sea Urchin Strong. purpuratus XP_783737 603 65189 N73 R Q P D E E E N E G G Q F G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 D257 L K G H N V F D E E E S D G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 13.3 100 13.3 N.A. 86.6 13.3 N.A. 0 6.6 6.6 20 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 26.6 100 40 N.A. 86.6 20 N.A. 6.6 20 13.3 20 N.A. 0 33.3 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 13 7 13 13 0 0 13 7 13 0 19 0 % A
% Cys: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 7 0 13 0 0 0 7 0 0 7 0 7 0 0 % D
% Glu: 0 7 0 13 13 13 7 0 25 13 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 7 0 13 0 0 7 0 13 % F
% Gly: 0 7 13 0 7 0 7 0 0 19 13 0 7 25 13 % G
% His: 0 0 7 32 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 0 7 0 7 0 0 0 0 0 0 % I
% Lys: 0 13 7 0 7 0 0 0 0 0 13 0 0 7 0 % K
% Leu: 13 0 25 7 0 0 7 7 0 0 7 25 13 13 25 % L
% Met: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 13 7 0 7 0 0 0 0 0 0 0 % N
% Pro: 7 13 7 7 7 13 13 7 13 0 19 7 32 0 7 % P
% Gln: 7 7 0 0 7 7 7 7 0 19 7 13 0 13 7 % Q
% Arg: 7 0 0 0 0 0 0 7 7 0 7 0 7 7 7 % R
% Ser: 38 0 7 0 25 7 0 25 25 0 7 25 19 7 0 % S
% Thr: 0 0 0 0 0 25 0 7 0 0 0 7 0 0 0 % T
% Val: 7 13 0 0 7 7 0 7 7 7 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 19 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _